Sequence Detail

ID/Version

Q9DBR7 Q05A74 Q99NB6 Q8CBV2 (UniProt | EBI)

Last sequence update: 2009-12-15
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein phosphatase 1 regulatory subunit 12A;AltName: Full=Myosin phosphatase-targeting subunit 1; Short=Myosin phosphatase target subunit 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1029 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ppp1r12a	protein phosphatase 1, regulatory subunit 12A	49	108	3	24

Sequence references in MGI

J:69997 Machida H, et al., Molecular cloning and analysis of the 5'-flanking region of the human MYPT1 gene. Biochim Biophys Acta. 2001 Feb 16;1517(3):424-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166394 Lontay B, et al., Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy. J Biol Chem. 2010 Sep 17;285(38):29357-66
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296646 Hughes JJ, et al., Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations. Am J Hum Genet. 2020 Jan 2;106(1):121-128