Sequence Detail

ID/Version

Q9DBX7 Q9QXW8 Q9JJV6 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Hairy/enhancer-of-split related with YRPW motif-like protein;AltName: Full=Hairy and enhancer of split-related protein 3;AltName: Full=Hairy-related transcription factor 3; Short=HRT-3; Short=mHRT3;

Provider

SWISS-PROT

Sequence

Polypeptide 326 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Heyl	hairy/enhancer-of-split related with YRPW motif-like	60	125	3	12

Sequence references in MGI

J:58781 Nakagawa O, et al., HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol. 1999 Dec 1;216(1):72-84
J:62860 Steidl C, et al., Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family. Genomics. 2000 Jun 1;66(2):195-203
J:65645 Leimeister C, et al., Analysis of HeyL expression in wild-type and notch pathway mutant mouse embryos. Mech Dev. 2000 Nov;98(1-2):175-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101349 Fischer A, et al., Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol. 2005 Oct;25(20):8960-70
J:109366 Satow T, et al., The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina. J Neurosci. 2001 Feb 15;21(4):1265-73
J:133699 Fischer A, et al., Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition. Circ Res. 2007 Mar 30;100(6):856-63