Sequence Detail

ID/Version

Q9DCP2 Q9JLL8 Q8BS53 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Sodium-coupled neutral amino acid transporter 3 {ECO:0000305};AltName: Full=N-system amino acid transporter 1;AltName: Full=Na(+)-coupled neutral amino acid transporter 3;AltName: Full=Solute carrier family 38 member 3; Short=mNAT {E

Provider

SWISS-PROT

Sequence

Polypeptide 505 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc38a3	solute carrier family 38, member 3	62	100	4	4

Sequence references in MGI

J:70748 Gu S, et al., Identification and characterization of an amino acid transporter expressed differentially in liver. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3230-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:150742 Busque SM, et al., Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney. Am J Physiol Renal Physiol. 2009 Aug;297(2):F440-50
J:234835 Chan K, et al., Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney. Pflugers Arch. 2016 Feb;468(2):213-27
J:289067 Dolgodilina E, et al., Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance. Fluids Barriers CNS. 2020 Feb 11;17(1):17
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:325963 Dong W, et al., PKC-Mediated Modulation of Astrocyte SNAT3 Glutamine Transporter Function at Synapses in Situ. Int J Mol Sci. 2018 Mar 21;19(4):924
J:326282 Umapathy NS, et al., Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Muller cells. Invest Ophthalmol Vis Sci. 2005 Nov;46(11):3980-7
J:326283 Umapathy NS, et al., Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):5151-60
J:326284 Gu S, et al., Differential regulation of amino acid transporter SNAT3 by insulin in hepatocytes. J Biol Chem. 2005 Jul 15;280(28):26055-62