Sequence Detail

ID/Version

Q9EP82 Q80V01 (UniProt | EBI)

Last sequence update: 2009-05-05
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056};AltName: Full=Protein Wuho homolog {ECO:0000303|PubMed:26751069}; Short=mWH {ECO:0000303|PubMed:26751069};AltName: Full=WD repeat-con

Provider

SWISS-PROT

Sequence

Polypeptide 413 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wdr4	WD repeat domain 4	21	103	3	29

Sequence references in MGI

J:64125 Michaud J, et al., Isolation and characterization of a human chromosome 21q22.3 gene (WDR4) and its mouse homologue that code for a WD-repeat protein. Genomics. 2000 Aug 15;68(1):71-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:230030 Cheng IC, et al., Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1. PLoS Biol. 2016 Jan;14(1):e1002349
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302077 Lee CC, et al., Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018 Jul;47:16-26