ID/Version |
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Sequence description from provider |
RecName: Full=Tumor necrosis factor receptor superfamily member 21;AltName: Full=Death receptor 6;AltName: CD_antigen=CD358;Flags: Precursor; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
655
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:70594
Liu J, et al., Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice. Immunity. 2001 Jul;15(1):23-34
J:72761 Zhao H, et al., Impaired c-Jun Amino Terminal Kinase Activity and T Cell Differentiation in Death Receptor 6-deficient Mice. J Exp Med. 2001 Nov 19;194(10):1441-8 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:109341 Schmidt CS, et al., Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6. J Exp Med. 2003 Jan 6;197(1):51-62 J:146602 Nikolaev A, et al., APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. (RETRACTION Nature https://doi.org/10.1038/nature07767). Nature. 2009 Feb 19;457(7232):981-9 J:205651 Mi S, et al., Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination. Nat Med. 2011 Jul;17(7):816-21 J:205745 Hu Y, et al., A DR6/p75(NTR) complex is responsible for beta-amyloid-induced cortical neuron death. Cell Death Dis. 2013;4:e579 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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