Sequence Detail

ID/Version

Q9EQ21 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Hepcidin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 83 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hamp	hepcidin antimicrobial peptide	64	102	3	16

Sequence references in MGI

J:67983 Pigeon C, et al., A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem. 2001 Mar 16;276(11):7811-9
J:70464 Nicolas G, et al., Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8780-5
J:121030 Nemeth E, et al., IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004 May;113(9):1271-6
J:211331 Kautz L, et al., Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014 Jul;46(7):678-84