ID/Version |
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Sequence description from provider |
RecName: Full=LRP chaperone MESD {ECO:0000305};AltName: Full=LDLR chaperone MESD;AltName: Full=Mesoderm development candidate 2;AltName: Full=Mesoderm development protein;Flags: Precursor; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
224
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:68210
Wines ME, et al., Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis. Genomics. 2001 Feb 15;72(1):88-98
J:82316 Hsieh JC, et al., Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell. 2003 Feb 7;112(3):355-67 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:175504 Chen J, et al., Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. Structure. 2011 Mar 9;19(3):313-23 J:202742 Hoshi T, et al., Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes. FEBS Lett. 2013 Nov 29;587(23):3749-54 J:243458 Chen X, et al., Mesd extrinsically promotes phagocytosis by retinal pigment epithelial cells. Cell Biol Toxicol. 2016 Aug;32(4):347-58 J:245302 Collins MN, et al., Structural characterization of the Boca/Mesd maturation factors for LDL-receptor-type beta propeller domains. Structure. 2011 Mar 09;19(3):324-36 J:287028 Moosa S, et al., Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. Am J Hum Genet. 2019 Oct 3;105(4):836-843 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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