Sequence Detail

ID/Version

Q9ESJ1 Q9EPR8 E9QNI6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=CDK5 and ABL1 enzyme substrate 1;AltName: Full=Interactor with CDK3 1; Short=Ik3-1;

Provider

SWISS-PROT

Sequence

Polypeptide 568 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cables1	CDK5 and Abl enzyme substrate 1	10	103	3	14

Sequence references in MGI

J:63117 Zukerberg LR, et al., Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron. 2000 Jun;26(3):633-46
J:63221 Matsuoka M, et al., Molecular cloning of a cyclin-like protein associated with cyclin-dependent kinase 3 (cdk 3) in vivo. Biochem Biophys Res Commun. 2000 Jul 5;273(2):442-7
J:114013 Tsuji K, et al., Differential effect of ik3-1/cables on p53- and p73-induced cell death. J Biol Chem. 2002 Jan 25;277(4):2951-7
J:168213 Wu CL, et al., Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers. Cancer Res. 2001 Oct 1;61(19):7325-32
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89