Sequence Detail

ID/Version

Q9ESN9 Q9ESN8 Q9ESP0 Q99KU7 Q9JLH3 Q9R0U7 Q9ESN7 Q9JLH2 Q9EQD8 Q5D062 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=C-Jun-amino-terminal kinase-interacting protein 3; Short=JIP-3; Short=JNK-interacting protein 3;AltName: Full=JNK MAP kinase scaffold protein 3;AltName: Full=JNK/SAPK-associated protein 1; Short=JSAP1;AltName: Full=Mi

Provider

SWISS-PROT

Sequence

Polypeptide 1337 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	74	109	3	9

Sequence references in MGI

J:59878 Kelkar N, et al., Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol Cell Biol. 2000 Feb;20(3):1030-43
J:64817 Ito M, et al., JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol Cell Biol. 1999 Nov;19(11):7539-48
J:65080 Ito M, et al., Isoforms of JSAP1 scaffold protein generated through alternative splicing. Gene. 2000 Sep 19;255(2):229-34
J:70979 Bowman AB, et al., Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 2000 Nov 10;103(4):583-94
J:114032 Verhey KJ, et al., Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J Cell Biol. 2001 Mar 5;152(5):959-70
J:199515 Sun T, et al., c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) regulates neuronal axon elongation in a kinesin- and JNK-dependent manner. J Biol Chem. 2013 May 17;288(20):14531-43
J:251170 Ma H, et al., JIP3 regulates neuronal radial migration by mediating TrkB axonal anterograde transport in the developing cerebral cortex. Biochem Biophys Res Commun. 2017 Apr 15;485(4):790-795
J:262353 Huang SH, et al., JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1. J Neurosci. 2011 Jul 20;31(29):10602-14
J:262360 Watt D, et al., JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation. J Biol Chem. 2015 Jun 19;290(25):15512-25
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89