Sequence Detail

ID/Version

Q9ESX5 Q3UWE5 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=H/ACA ribonucleoprotein complex subunit DKC1; EC=5.4.99.- {ECO:0000250|UniProtKB:O60832};AltName: Full=Dyskerin;AltName: Full=Nopp140-associated protein of 57 kDa;AltName: Full=Nucleolar protein NAP57;AltName: Full=Nucleolar protein

Provider

SWISS-PROT

Sequence

Polypeptide 509 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dkc1	dyskeratosis congenita 1, dyskerin	54	100	3	16

Sequence references in MGI

J:63601 Heiss NS, et al., Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics. 2000 Jul 15;67(2):153-63
J:81054 Ruggero D, et al., Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science. 2003 Jan 10;299(5604):259-62
J:91485 Mochizuki Y, et al., Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10756-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89