Sequence Detail

ID/Version

Q9JHJ3 Q8C6H7 Q3UBV7 Q3TUF5 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Glycosylated lysosomal membrane protein {ECO:0000312|MGI:MGI:1913318};AltName: Full=Lysosomal protein NCU-G1 {ECO:0000305};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 404 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Glmp	glycosylated lysosomal membrane protein	14	100	3	13

Sequence references in MGI

J:70003 Kawamura T, et al., cDNA of a novel mRNA expressed predominantly in mouse kidney. Biochem Genet. 2001 Feb;39(1-2):33-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:150969 Schieweck O, et al., NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. Biochem J. 2009 Aug 15;422(1):83-90
J:208774 Kong XY, et al., Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells. Dis Model Mech. 2014 Mar;7(3):351-62
J:237709 Kong XY, et al., Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver. PLoS One. 2015;10(6):e0129402
J:280713 Massa Lopez D, et al., The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP. Elife. 2019 Oct 29;8:e50025
J:297335 Lopez DM, et al., Characterization of the complex of the lysosomal membrane transporter MFSD1 and its accessory subunit GLMP. FASEB J. 2020 Nov;34(11):14695-14709