Sequence Detail

ID/Version

Q9JHS3 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ragulator complex protein LAMTOR2;AltName: Full=Endosomal adaptor protein p14;AltName: Full=Late endosomal/lysosomal Mp1-interacting protein;AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2;AltName: Full=Mitogen-a

Provider

SWISS-PROT

Sequence

Polypeptide 125 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lamtor2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	40	96	3	51

Sequence references in MGI

J:67536 Wunderlich W, et al., A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J Cell Biol. 2001 Feb 19;152(4):765-76
J:90682 Lunin VV, et al., The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling. J Biol Chem. 2004 May 28;279(22):23422-30
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116248 Kurzbauer R, et al., Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10984-9
J:168293 Nada S, et al., The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes. EMBO J. 2009 Mar 4;28(5):477-89
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89