Sequence Detail

ID/Version

Q9JI10 Q8CI58 Q80UG4 Q60877 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase 3; EC=2.7.11.1;AltName: Full=Mammalian STE20-like protein kinase 2; Short=MST-2;AltName: Full=STE20-like kinase MST2;Contains: RecName: Full=Serine/threonine-protein kinase 3 36kDa subunit;

Provider

SWISS-PROT

Sequence

Polypeptide 497 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stk3	serine/threonine kinase 3	77	100	3	21

Sequence references in MGI

J:69763 Lee KK, et al., MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J Biol Chem. 2001 Jun 1;276(22):19276-85
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:156531 Lu L, et al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1437-42
J:169049 Varelas X, et al., The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev Cell. 2010 Dec 14;19(6):831-44
J:238700 Kwan J, et al., DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. Genes Dev. 2016 Dec 15;30(24):2696-2709
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89