Sequence Detail

ID/Version

Q9JIP4 Q9CXS7 Q5RL18 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Pannexin-1;Contains: RecName: Full=Caspase-activated pannexin-1 {ECO:0000303|PubMed:32238926}; Short=Caspase-activated PANX1 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 426 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Panx1	pannexin 1	52	106	4	23

Sequence references in MGI

J:62853 Panchin Y, et al., A ubiquitous family of putative gap junction molecules. Curr Biol. 2000 Jun 29;10(13):R473-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:128467 Penuela S, et al., Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J Cell Sci. 2007 Nov 1;120(Pt 21):3772-83
J:277894 DeLalio LJ, et al., Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane. J Biol Chem. 2019 Apr 26;294(17):6940-6956
J:293231 Medina CB, et al., Metabolites released from apoptotic cells act as tissue messengers. Nature. 2020 Apr;580(7801):130-135
J:345438 Ma W, et al., Pannexin 1 forms an anion-selective channel. Pflugers Arch. 2012 Apr;463(4):585-92