Sequence Detail

ID/Version

Q9JJ00 O54730 O54731 Q9D1F8 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Phospholipid scramblase 1; Short=PL scramblase 1;AltName: Full=Ca(2+)-dependent phospholipid scramblase 1;AltName: Full=Mg(2+)-dependent nuclease {ECO:0000250|UniProtKB:O15162}; EC=3.1.-.- {ECO:0000250|UniProtKB:O15162};AltNa

Provider

SWISS-PROT

Sequence

Polypeptide 328 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plscr1	phospholipid scramblase 1	92	97	6	14

Sequence references in MGI

J:39827 Kasukabe T, et al., TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines. Blood. 1997 Apr 15;89(8):2975-85
J:62780 Wiedmer T, et al., Identification of three new members of the phospholipid scramblase gene family. Biochim Biophys Acta. 2000 Jul 31;1467(1):244-53
J:76790 Zhou Q, et al., Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1. Blood. 2002 Jun 1;99(11):4030-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:252403 Herate C, et al., Phospholipid Scramblase 1 Modulates FcR-Mediated Phagocytosis in Differentiated Macrophages. PLoS One. 2016;11(1):e0145617
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:292529 Guo J, et al., Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis. Cells. 2020 Feb 26;9(3):547
J:325499 Liu Y, et al., ILDR1 promotes influenza A virus replication through binding to PLSCR1. Sci Rep. 2022 May 20;12(1):8515