Sequence Detail

ID/Version

Q9JJJ3 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Aquaporin-9 {ECO:0000305|PubMed:10777495}; Short=AQP-9 {ECO:0000305|PubMed:10777495};AltName: Full=Aquaglyceroporin-9 {ECO:0000305|PubMed:10777495};

Provider

SWISS-PROT

Sequence

Polypeptide 295 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aqp9	aquaporin 9	53	125	3	10

Sequence references in MGI

J:65722 Kishida K, et al., Aquaporin adipose, a putative glycerol channel in adipocytes. J Biol Chem. 2000 Jul 7;275(27):20896-902
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:123742 Rojek AM, et al., Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3609-14
J:153240 Carbrey JM, et al., Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15956-60
J:178825 Jelen S, et al., Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice. J Biol Chem. 2011 Dec 30;286(52):44319-25
J:193645 Jelen S, et al., Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 1;303(11):G1279-87
J:233327 Watanabe S, et al., Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells. Biochem Biophys Res Commun. 2016 Feb 26;471(1):191-7
J:310469 Mori S, et al., Aqp9 Gene Deletion Enhances Retinal Ganglion Cell (RGC) Death and Dysfunction Induced by Optic Nerve Crush: Evidence that Aquaporin 9 Acts as an Astrocyte-to-Neuron Lactate Shuttle in Concert with Monocarboxylate Transporters To Support RGC Function and Survival. Mol Neurobiol. 2020 Nov;57(11):4530-4548
J:355656 Liu Z, et al., Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6053-8