Sequence Detail

ID/Version

Q9JJN1 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Fibroblast growth factor 21; Short=FGF-21;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 210 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fgf21	fibroblast growth factor 21	26	116	3	17

Sequence references in MGI

J:63008 Nishimura T, et al., Identification of a novel FGF, FGF-21, preferentially expressed in the liver(1). Biochim Biophys Acta. 2000 Jun 21;1492(1):203-6
J:99202 Kharitonenkov A, et al., FGF-21 as a novel metabolic regulator. J Clin Invest. 2005 Jun;115(6):1627-35
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:270482 Wei J, et al., HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination. EMBO J. 2018 Nov 15;37(22)
J:284081 Turpin-Nolan SM, et al., CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7