Sequence Detail

ID/Version

Q9JKQ4 Q9JLL5 Q80WV4 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Iroquois-class homeodomain protein IRX-5;AltName: Full=Homeodomain protein IRXB2;AltName: Full=Iroquois homeobox protein 5;

Provider

SWISS-PROT

Sequence

Polypeptide 484 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irx5	Iroquois homeobox 5	22	122	4	9

Sequence references in MGI

J:61328 Cohen DR, et al., Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21
J:62062 Bosse A, et al., Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family. Dev Dyn. 2000 May;218(1):160-74
J:64020 Christoffels VM, et al., Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart. Dev Biol. 2000 Aug 15;224(2):263-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103461 Cheng CW, et al., The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development. Dev Biol. 2005 Nov 1;287(1):48-60
J:115194 Costantini DL, et al., The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 2005 Oct 21;123(2):347-58
J:125316 Reggiani L, et al., The prepattern transcription factor Irx3 directs nephron segment identity. Genes Dev. 2007 Sep 15;21(18):2358-70
J:132777 Kerschensteiner D, et al., Genetic control of circuit function: Vsx1 and Irx5 transcription factors regulate contrast adaptation in the mouse retina. J Neurosci. 2008 Mar 5;28(10):2342-52