Sequence Detail

ID/Version

Q9JL27 O70504 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Galactoside alpha-(1,2)-fucosyltransferase 2 {ECO:0000305};AltName: Full=Alpha(1,2)FT 2;AltName: Full=Fucosyltransferase 2;AltName: Full=GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2;AltName: Full=GDP-fucose: beta-galactosid

Provider

SWISS-PROT

Sequence

Polypeptide 347 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fut2	fucosyltransferase 2	21	98	2	13

Sequence references in MGI

J:66377 Lin B, et al., GDP-fucose: beta-galactoside alpha1,2-fucosyltransferase, MFUT-II, and not MFUT-I or -III, is induced in a restricted region of the digestive tract of germ-free mice by host-microbe interactions and cycloheximide. Biochim Biophys Acta. 2000 Sep 27;1487(2-3):275-85
J:68898 Lin B, et al., Characterization of three members of murine alpha1,2-fucosyltransferases: change in the expression of the Se gene in the intestine of mice after administration of microbes. Arch Biochem Biophys. 2001 Apr 15;388(2):207-15
J:70130 Domino SE, et al., Molecular cloning, genomic mapping, and expression of two secretor blood group alpha (1,2)fucosyltransferase genes differentially regulated in mouse uterine epithelium and gastrointestinal tract. J Biol Chem. 2001 Jun 29;276(26):23748-56
J:72946 Domino SE, et al., Deficiency of Reproductive Tract alpha(1,2)Fucosylated Glycans and Normal Fertility in Mice with Targeted Deletions of the FUT1 or FUT2 alpha(1,2)Fucosyltransferase Locus. Mol Cell Biol. 2001 Dec;21(24):8336-45
J:89929 Iwamori M, et al., Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes. Biochem J. 2004 May 15;380(Pt 1):75-81
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:229659 Magalhaes A, et al., Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa. Glycobiology. 2009 Dec;19(12):1525-36
J:244876 Magalhaes A, et al., Muc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori binding. Sci Rep. 2016 May 10;6:25575