Sequence Detail

ID/Version

Q9JLA2 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Interleukin-36 alpha;AltName: Full=FIL1 epsilon;AltName: Full=Interleukin-1 epsilon; Short=IL-1 epsilon;AltName: Full=Interleukin-1 family member 6; Short=IL-1F6;AltName: Full=Interleukin-1 homolog 1; Short=IL-1H1;Fla

Provider

SWISS-PROT

Sequence

Polypeptide 160 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il36a	interleukin 36A	17	96	3	8

Sequence references in MGI

J:61590 Kumar S, et al., Identification and initial characterization of four novel members of the interleukin-1 family. J Biol Chem. 2000 Apr 7;275(14):10308-14
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:157690 Ichii O, et al., Local overexpression of interleukin-1 family, member 6 relates to the development of tubulointerstitial lesions. Lab Invest. 2010 Mar;90(3):459-75
J:178804 Vigne S, et al., IL-36R ligands are potent regulators of dendritic and T cells. Blood. 2011 Nov 24;118(22):5813-23
J:191979 Ramadas RA, et al., IL-36alpha exerts pro-inflammatory effects in the lungs of mice. PLoS One. 2012;7(9):e45784