Sequence Detail

ID/Version

Q9JLJ0 Q9EQI0 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; Short=LPS-induced TNF-alpha factor homolog;AltName: Full=Estrogen-enhanced transcript protein {ECO:0000303|PubMed:12355436}; Short=mEET {ECO:0000303|PubMe

Provider

SWISS-PROT

Sequence

Polypeptide 161 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Litaf	LPS-induced TN factor	40	104	3	24

Sequence references in MGI

J:65663 Jolliffe CN, et al., Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase nedd4. Biochem J. 2000 Nov 1;351 Pt 3:557-65
J:89464 Bolcato-Bellemin AL, et al., Molecular cloning and characterization of mouse LITAF cDNA: role in the regulation of tumor necrosis factor-alpha (TNF-alpha) gene expression. J Endotoxin Res. 2004;10(1):15-23
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113750 Tang X, et al., LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways. Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13777-82
J:180147 Merrill JC, et al., Whole-body deletion of LPS-induced TNF-alpha factor (LITAF) markedly improves experimental endotoxic shock and inflammatory arthritis. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21247-52
J:186411 Somandin C, et al., LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: Implications for Charcot-Marie-Tooth disease. Glia. 2012 Oct;60(10):1518-28
J:195246 Lee SM, et al., Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking. J Cell Biol. 2012 Nov 26;199(5):799-816
J:244629 Tang X, et al., Novel regulation of CCL2 gene expression by murine LITAF and STAT6B. PLoS One. 2011;6(9):e25083