Sequence Detail

ID/Version

Q9JLJ1 Q8CI00 (UniProt | EBI)

Last sequence update: 2008-02-26
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Selenoprotein K {ECO:0000303|PubMed:21849499}; Short=SelK {ECO:0000303|PubMed:21849499};

Provider

SWISS-PROT

Sequence

Polypeptide 94 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Selenok	selenoprotein K	35	98	3	12

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:169169 Verma S, et al., Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses. J Immunol. 2011 Feb 15;186(4):2127-37
J:177589 Huang Z, et al., Selenoprotein K is a novel target of m-calpain, and cleavage is regulated by Toll-like receptor-induced calpastatin in macrophages. J Biol Chem. 2011 Oct 7;286(40):34830-8
J:180698 Shchedrina VA, et al., Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis. J Biol Chem. 2011 Dec 16;286(50):42937-48
J:200795 Meiler S, et al., Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis. J Leukoc Biol. 2013 May;93(5):771-80
J:216755 Fredericks GJ, et al., Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16478-83