Sequence Detail

ID/Version

Q9JLJ5 Q9D1B2 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Very long chain fatty acid elongase 1 {ECO:0000255|HAMAP-Rule:MF_03201}; EC=2.3.1.199 {ECO:0000255|HAMAP-Rule:MF_03201, ECO:0000269|PubMed:20937905, ECO:0000269|PubMed:23689133};AltName: Full=3-keto acyl-CoA synthase Elovl1 {ECO:0000

Provider

SWISS-PROT

Sequence

Polypeptide 279 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Elovl1	ELOVL fatty acid elongase 1	24	103	4	14

Sequence references in MGI

J:61900 Tvrdik P, et al., Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids. J Cell Biol. 2000 May 1;149(3):707-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:165504 Ohno Y, et al., ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18439-44
J:194257 Li S, et al., Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase. J Neurosci. 2013 Feb 13;33(7):3178-89
J:204477 Sassa T, et al., Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Mol Cell Biol. 2013 Jul;33(14):2787-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89