Sequence Detail

ID/Version

Q9JM05 Q8R165 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=E3 SUMO-protein ligase PIAS4; EC=2.3.2.27;AltName: Full=PIASy {ECO:0000303|PubMed:11731474};AltName: Full=Protein inhibitor of activated STAT protein 4;AltName: Full=Protein inhibitor of activated STAT protein gamma; Short=PI

Provider

SWISS-PROT

Sequence

Polypeptide 507 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pias4	protein inhibitor of activated STAT 4	49	110	4	9

Sequence references in MGI

J:63546 Sturm S, et al., Cloning and analysis of a murine PIAS family member, PIASgamma, in developing skin and neurons. J Mol Neurosci. 2000 Feb-Apr;14(1-2):107-21
J:73179 Sachdev S, et al., PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev. 2001 Dec 1;15(23):3088-103
J:172990 Albor A, et al., The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB. J Biol Chem. 2006 Sep 1;281(35):25850-66
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89