ID/Version |
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Sequence description from provider |
RecName: Full=Pancreas transcription factor 1 subunit alpha;AltName: Full=Pancreas-specific transcription factor 1a;AltName: Full=bHLH transcription factor p48;AltName: Full=p48 DNA-binding subunit of transcription factor PTF1; Short=PTF1-p48; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
324
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:51571
Krapp A, et al., The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev. 1998 Dec 1;12(23):3752-63
J:62777 Obata J, et al., p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes Cells. 2001 Apr;6(4):345-60 J:72789 Rose SD, et al., The Role of PTF1-P48 in Pancreatic Acinar Gene Expression. J Biol Chem. 2001 Nov 23;276(47):44018-26 J:78710 Kawaguchi Y, et al., The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet. 2002 Sep;32(1):128-34 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:115271 Fujitani Y, et al., Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development. 2006 Nov;133(22):4439-50 J:120017 Sellick GS, et al., Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat Genet. 2004 Dec;36(12):1301-5 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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