Sequence Detail

ID/Version

Q9QXE0 Q543K1 Q9DAV1 (UniProt | EBI)

Last sequence update: 2002-05-02
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=2-hydroxyacyl-CoA lyase 1; EC=4.1.2.63 {ECO:0000269|PubMed:28629946};AltName: Full=2-hydroxyphytanoyl-CoA lyase; Short=2-HPCL;AltName: Full=Phytanoyl-CoA 2-hydroxylase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 581 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hacl1	2-hydroxyacyl-CoA lyase 1	39	100	3	5

Sequence references in MGI

J:67589 Huyghe S, et al., Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J. 2001 Feb 1;353(Pt 3):673-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:255067 Mezzar S, et al., Phytol-induced pathology in 2-hydroxyacyl-CoA lyase (HACL1) deficient mice. Evidence for a second non-HACL1-related lyase. Biochim Biophys Acta. 2017 Sep;1862(9):972-990
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89