Sequence Detail

ID/Version

Q9QXG4 Q8BK97 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Acetyl-coenzyme A synthetase, cytoplasmic; EC=6.2.1.1 {ECO:0000269|PubMed:11150295, ECO:0000269|PubMed:16790548, ECO:0000269|PubMed:28562591};AltName: Full=Acetate--CoA ligase;AltName: Full=Acetyl-CoA synthetase; Short=ACS;

Provider

SWISS-PROT

Sequence

Polypeptide 701 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acss2	acyl-CoA synthetase short-chain family member 2	24	105	3	12

Sequence references in MGI

J:72156 Fujino T, et al., Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate. J Biol Chem. 2001 Apr 6;276(14):11420-6
J:77316 Loikkanen I, et al., Expression of cytosolic acetyl-CoA synthetase gene is developmentally regulated. Mech Dev. 2002 Jul;115(1-2):139-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:249263 Mews P, et al., Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature. 2017 Jun 15;546(7658):381-386
J:256787 Li X, et al., Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017 Jun 1;66(5):684-697.e9
J:276379 Hallows WC, et al., Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10230-10235
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89