Sequence Detail

ID/Version

Q9QXZ9 B2C712 A4QPG3 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Melanopsin;AltName: Full=Opsin-4;

Provider

SWISS-PROT

Sequence

Polypeptide 521 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Opn4	opsin 4 (melanopsin)	37	101	5	19

Sequence references in MGI

J:59329 Provencio I, et al., A novel human opsin in the inner retina. J Neurosci. 2000 Jan 15;20(2):600-5
J:81604 Hattar S, et al., Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science. 2002 Feb 8;295(5557):1065-70
J:84281 Hattar S, et al., Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature. 2003 Jul 3;424(6944):75-81
J:158237 Pires SS, et al., Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina. J Neurosci. 2009 Sep 30;29(39):12332-42
J:227078 Buhr ED, et al., Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13093-8
J:279052 Nguyen MT, et al., An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nat Cell Biol. 2019 Apr;21(4):420-429
J:280968 Buhr ED, et al., Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin. Curr Biol. 2019 Oct 21;29(20):3478-3487.e4
J:281284 Ota W, et al., Impaired Circadian Photoentrainment in Opn5-Null Mice. iScience. 2018 Aug 31;6:299-305