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Sequence Detail
ID/Version
Q9QY23 Q3KQL7 Q0VGP3 A4QPD8 (UniProt | EBI) Last sequence update: 2007-06-12
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Plakophilin-3;
Provider SWISS-PROT
Sequence
Polypeptide 797 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Pkp3 plakophilin 3 48 98 4 8
Sequence references in MGI J:64912 Bonne S, et al., Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells. J Cell Sci. 1999 Jul;112(Pt 14):2265-76
J:136451 Sklyarova T, et al., Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation. J Invest Dermatol. 2008 Jun;128(6):1375-85
J:233047 Sklyarova T, et al., Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice. Eur J Immunol. 2015 Oct;45(10):2898-910
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:352393 Muller L, et al., Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling. Cell Rep. 2023 Jan 31;42(1):112031

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory