Sequence Detail

ID/Version

Q9QYK5 Q3TK52 Q3TND4 Q3TKK0 Q3TZT5 (UniProt | EBI)

Last sequence update: 2009-05-05
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Heparan-sulfate 6-O-sulfotransferase 1 {ECO:0000305}; Short=HS6ST-1; Short=mHS6ST-1; EC=2.8.2.- {ECO:0000269|PubMed:10644753};

Provider

SWISS-PROT

Sequence

Polypeptide 411 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	14	109	4	17

Sequence references in MGI

J:60682 Habuchi H, et al., The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine. J Biol Chem. 2000 Jan 28;275(4):2859-68
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122656 Habuchi H, et al., Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality. J Biol Chem. 2007 May 25;282(21):15578-88
J:135241 Izvolsky KI, et al., Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan;46(1):8-18