ID/Version |
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Sequence description from provider |
RecName: Full=Doublesex- and mab-3-related transcription factor 1; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
374
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:58410
Raymond CS, et al., Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development. Dev Biol. 1999 Nov 15;215(2):208-20
J:58958 Smith CA, et al., Conservation of a sex-determining gene. Nature. 1999 Dec 9;402(6762):601-2 J:60422 De Grandi A, et al., The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation. Mech Dev. 2000 Feb;90(2):323-6 J:65541 Raymond CS, et al., Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 2000 Oct 15;14(20):2587-95 J:116624 Lu H, et al., Multiple alternative splicing of mouse Dmrt1 during gonadal differentiation. Biochem Biophys Res Commun. 2007 Jan 19;352(3):630-4 J:122954 Kim S, et al., Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation. Dev Biol. 2007 Jul 15;307(2):314-27 J:156489 Krentz AD, et al., The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8 J:162401 Murphy MW, et al., Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13360-5 J:166057 Matson CK, et al., The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells. Dev Cell. 2010 Oct 19;19(4):612-24 J:174935 Matson CK, et al., DMRT1 prevents female reprogramming in the postnatal mammalian testis. Nature. 2011 Aug 4;476(7358):101-4 J:175257 Krentz AD, et al., DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary. Dev Biol. 2011 Aug 1;356(1):63-70 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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