Sequence Detail

ID/Version

Q9R118 Q8BN05 Q91WS3 Q8BN04 Q9QZK6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Serine protease HTRA1; EC=3.4.21.-;AltName: Full=High-temperature requirement A serine peptidase 1;AltName: Full=Serine protease 11;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 480 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Htra1	HtrA serine peptidase 1	26	121	4	53

Sequence references in MGI

J:88556 Oka C, et al., HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Development. 2004 Mar;131(5):1041-53
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:154267 Launay S, et al., HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival. Cell Death Differ. 2008 Sep;15(9):1408-16
J:179693 Zhang L, et al., High Temperature Requirement Factor A1 (HTRA1) Gene Regulates Angiogenesis through Transforming Growth Factor-beta Family Member Growth Differentiation Factor 6. J Biol Chem. 2012 Jan 6;287(2):1520-6
J:225932 Tsuchiya A, et al., Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis. Bone. 2005 Sep;37(3):323-36