Sequence Detail

ID/Version

Q9R144 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Protein arginine N-methyltransferase 2; EC=2.1.1.319 {ECO:0000250|UniProtKB:P55345};AltName: Full=Histone-arginine N-methyltransferase PRMT2;

Provider

SWISS-PROT

Sequence

Polypeptide 448 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prmt2	protein arginine N-methyltransferase 2	64	104	3	15

Sequence references in MGI

J:109065 Ganesh L, et al., Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis. Mol Cell Biol. 2006 May;26(10):3864-74
J:111352 Yoshimoto T, et al., The arginine methyltransferase PRMT2 binds RB and regulates E2F function. Exp Cell Res. 2006 Jul 1;312(11):2040-53
J:178194 Iwasaki H, et al., Disruption of protein arginine N-methyltransferase 2 regulates leptin signaling and produces leanness in vivo through loss of STAT3 methylation. Circ Res. 2010 Oct 15;107(8):992-1001
J:190282 Blythe SA, et al., beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220-31