Sequence Detail

ID/Version

Q9R1E6 B2ZP54 A8UH93 A8UH85 Q99LG9 Q6PDE0 (UniProt | EBI)

Last sequence update: 2009-02-10
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Autotaxin {ECO:0000303|PubMed:18175805}; EC=3.1.4.39 {ECO:0000269|PubMed:17208043, ECO:0000269|PubMed:18175805, ECO:0000269|PubMed:21240269, ECO:0000269|PubMed:23688339, ECO:0000269|PubMed:27780639}; EC=3.1.4.4 {ECO:0000250|U

Provider

SWISS-PROT

Sequence

Polypeptide 862 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Enpp2	ectonucleotide pyrophosphatase/phosphodiesterase 2	53	132	3	19

Sequence references in MGI

J:60952 Piao JH, et al., Assignment of Pdnp2, the gene encoding phosphodiesterase I/nucleotide pyrophosphatase 2, to mouse chromosome 15D2. Cytogenet Cell Genet. 1999;87(3-4):172-4
J:83030 Gijsbers R, et al., Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1. Biochem J. 2003 Apr 15;371(Pt 2):321-30
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:120280 Pradere JP, et al., Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase. Biochim Biophys Acta. 2007 Jan;1771(1):93-102
J:133793 Giganti A, et al., Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization. J Biol Chem. 2008 Mar 21;283(12):7776-89
J:173719 Nishimasu H, et al., Crystal structure of autotaxin and insight into GPCR activation by lipid mediators. Nat Struct Mol Biol. 2011 Feb;18(2):205-12
J:190295 Kato K, et al., Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16876-81
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89