Sequence Detail

ID/Version

Q9R1S7 A2TAJ0 A2TAJ1 Q80YB6 F8VPT2 (UniProt | EBI)

Last sequence update: 2011-12-14
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=ATP-binding cassette sub-family C member 6; EC=7.6.2.- {ECO:0000250|UniProtKB:O88269}; EC=7.6.2.3 {ECO:0000250|UniProtKB:O95255};AltName: Full=Multidrug resistance-associated protein 6;

Provider

SWISS-PROT

Sequence

Polypeptide 1498 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abcc6	ATP-binding cassette, sub-family C member 6	69	101	5	24

Sequence references in MGI

J:105062 Gorgels TG, et al., Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum. Hum Mol Genet. 2005 Jul 1;14(13):1763-73
J:120144 Meng H, et al., Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4530-5
J:205185 Jansen RS, et al., ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20206-11
J:213284 Pomozi V, et al., ABCC6 is a basolateral plasma membrane protein. Circ Res. 2013 May 24;112(11):e148-51
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89