Sequence Detail

ID/Version

Q9R229 Q9Z1V8 A6H6S5 (UniProt | EBI)

Last sequence update: 2007-11-13
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Bone morphogenetic protein 10; Short=BMP-10;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 421 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmp10	bone morphogenetic protein 10	59	117	4	17

Sequence references in MGI

J:53506 Neuhaus H, et al., Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech Dev. 1999 Feb;80(2):181-4
J:89404 Pashmforoush M, et al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell. 2004 Apr 30;117(3):373-86
J:89476 Chen H, et al., BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004 May;131(9):2219-31
J:116941 Chen H, et al., Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth. J Biol Chem. 2006 Sep 15;281(37):27481-91
J:176620 Castonguay R, et al., Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011 Aug 26;286(34):30034-46
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89