ID/Version |
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Sequence description from provider |
RecName: Full=Nuclear protein 1 {ECO:0000305};AltName: Full=Protein p8 {ECO:0000303|Ref.1}; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
80
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:99680
The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:133728 Vasseur S, et al., p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene. 2002 Mar 7;21(11):1685-94 J:140899 Million Passe CM, et al., Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod. 2008 Oct;79(4):598-607 J:153063 Sambasivan R, et al., The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter. J Cell Sci. 2009 Oct 1;122(Pt 19):3481-91 J:156137 Plant SR, et al., Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia. 2006 Apr 1;53(5):529-37 J:188293 Hamidi T, et al., Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. J Clin Invest. 2012 Jun 1;122(6):2092-103 J:203693 Barbosa-Sampaio HC, et al., Nupr1 deletion protects against glucose intolerance by increasing beta cell mass. Diabetologia. 2013 Nov;56(11):2477-86 J:271708 Galichon P, et al., Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo. J Am Soc Nephrol. 2017 Feb;28(2):545-556 J:271800 Kong DK, et al., Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function. Mol Biol Cell. 2010 Apr 15;21(8):1335-49 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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