Sequence Detail

ID/Version

Q9WTW5 Q9R209 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Solute carrier family 22 member 3 {ECO:0000303|PubMed:9933568};AltName: Full=Organic cation transporter 3 {ECO:0000303|PubMed:10966924}; Short=OCT3 {ECO:0000303|PubMed:10966924};

Provider

SWISS-PROT

Sequence

Polypeptide 551 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc22a3	solute carrier family 22 (organic cation transporter), member 3	89	111	3	4

Sequence references in MGI

J:52875 Verhaagh S, et al., Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27. Genomics. 1999 Jan 15;55(2):209-18
J:64862 Wu X, et al., Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. Am J Physiol Renal Physiol. 2000 Sep;279(3):F449-58
J:138641 Vialou V, et al., Altered aminergic neurotransmission in the brain of organic cation transporter 3-deficient mice. J Neurochem. 2008 Aug;106(3):1471-82
J:148392 Cui M, et al., The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway. Proc Natl Acad Sci U S A. 2009 May 12;106(19):8043-8
J:333164 Gasser PJ, et al., Organic cation transporter 3 (OCT3) is localized to intracellular and surface membranes in select glial and neuronal cells within the basolateral amygdaloid complex of both rats and mice. Brain Struct Funct. 2017 May;222(4):1913-1928