Sequence Detail

ID/Version

Q9WTX6 Q9WUI7 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Cullin-1; Short=CUL-1;

Provider

SWISS-PROT

Sequence

Polypeptide 776 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cul1	cullin 1	37	102	4	64

Sequence references in MGI

J:48258 Michel JJ, et al., Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 1998 Jun;9(6):435-49
J:54020 Hatakeyama S, et al., Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3859-63
J:57767 Dealy MJ, et al., Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat Genet. 1999 Oct;23(2):245-8
J:73276 Maruyama S, et al., Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10. Genomics. 2001 Dec;78(3):214-22
J:111403 Tsunematsu R, et al., Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. Mol Cell Biol. 2006 Aug;26(16):6157-69
J:163142 Yoshida Y, et al., E3 ubiquitin ligase that recognizes sugar chains. Nature. 2002 Jul 25;418(6896):438-42
J:194037 Yoo SH, et al., Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm. Cell. 2013 Feb 28;152(5):1091-105
J:196293 Hirano A, et al., FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes. Cell. 2013 Feb 28;152(5):1106-18
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87