Sequence Detail

ID/Version

Q9WTZ1 Q3UKF8 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=RING-box protein 2 {ECO:0000303|PubMed:24210661}; Short=Rbx2 {ECO:0000303|PubMed:24210661}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9UBF6}; EC=2.3.2.32 {ECO:0000250|UniProtKB:Q9UBF6};AltName: Full=RING finger protein 7;Al

Provider

SWISS-PROT

Sequence

Polypeptide 113 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rnf7	ring finger protein 7	32	106	3	26

Sequence references in MGI

J:53898 Duan H, et al., SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents. Mol Cell Biol. 1999 Apr;19(4):3145-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:178926 Tan M, et al., SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation. Dev Cell. 2011 Dec 13;21(6):1062-76
J:205551 Simo S, et al., Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors. Dev Cell. 2013 Nov 25;27(4):399-411
J:257927 Fairchild CL, et al., RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283
J:352580 Lumpkin RJ, et al., Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nat Commun. 2020 Jun 8;11(1):2866