Sequence Detail

ID/Version

Q9WU56 Q9EQD1 Q3UUC6 Q8C250 Q8VDQ3 Q9JJE5 Q791J1 (UniProt | EBI)

Last sequence update: 2006-09-05
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Pseudouridylate synthase 1 homolog {ECO:0000305}; EC=5.4.99.- {ECO:0000269|PubMed:10094309, ECO:0000269|PubMed:15327771};AltName: Full=tRNA pseudouridine synthase 1 {ECO:0000305}; EC=5.4.99.12 {ECO:0000269|PubMed:10094309};Al

Provider

SWISS-PROT

Sequence

Polypeptide 423 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pus1	pseudouridine synthase 1	32	96	3	18

Sequence references in MGI

J:66334 Chen J, et al., Mouse pseudouridine synthase 1: gene structure and alternative splicing of pre-mRNA. Biochem J. 2000 Dec 1;352 Pt 2:465-73
J:66589 Chen J, et al., Cloning and characterization of a mammalian pseudouridine synthase. RNA. 1999 Mar;5(3):409-19
J:92505 Zhao X, et al., Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator. Mol Cell. 2004 Aug 27;15(4):549-58
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:237107 Mangum JE, et al., Pseudouridine synthase 1 deficient mice, a model for Mitochondrial Myopathy with Sideroblastic Anemia, exhibit muscle morphology and physiology alterations. Sci Rep. 2016 May 20;6:26202
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89