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Sequence Detail
ID/Version
Q9WUQ2 Q9QZ99 (UniProt | EBI) Last sequence update: 1999-11-01
Last annotation update: 2024-05-29
Sequence
description
from provider
RecName: Full=Guanine nucleotide-exchange factor SEC12 {ECO:0000305|PubMed:11422940};AltName: Full=Mammalian guanine nucleotide exchange factor Sec12 {ECO:0000303|PubMed:11422940}; Short=mSec12 {ECO:0000303|PubMed:11422940};AltName: Full=Prolactin
Provider SWISS-PROT
Sequence
Polypeptide 417 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Preb prolactin regulatory element binding 23 104 3 11
Sequence references in MGI J:60870 Taylor Clelland CL, et al., Mapping and developmental expression analysis of the WD-repeat gene preb. Genomics. 2000 Feb 1;63(3):391-9
J:233589 Weissman JT, et al., The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export. Traffic. 2001 Jul;2(7):465-75
J:285677 Su L, et al., Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019 Apr 15;38(8)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory