Sequence Detail

ID/Version

Q9WUZ9 O70214 Q8CD29 Q544J4 Q8BR23 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 5 {ECO:0000305|PubMed:10369669, ECO:0000305|PubMed:21074248}; Short=NTPDase 5; EC=3.6.1.6 {ECO:0000269|PubMed:10369669, ECO:0000269|PubMed:21074248};AltName: Full=CD39 antigen-li

Provider

SWISS-PROT

Sequence

Polypeptide 427 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	25	103	4	9

Sequence references in MGI

J:45879 Chadwick BP, et al., cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases. Mamm Genome. 1998 Feb;9(2):162-4
J:59545 Recio JA, et al., cDNA isolation, expression, and chromosomal localization of the mouse pcph proto-oncogene. Mol Carcinog. 1999 Oct;26(2):130-6
J:65756 Trombetta ES, et al., Glycoprotein reglucosylation and nucleotide sugar utilization in the secretory pathway: identification of a nucleoside diphosphatase in the endoplasmic reticulum. EMBO J. 1999 Jun 15;18(12):3282-92
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:163795 Read R, et al., Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest. Vet Pathol. 2009 May;46(3):491-504
J:167903 Fang M, et al., The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell. 2010 Nov 24;143(5):711-24
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89