Sequence Detail

ID/Version

Q9WVC6 Q3V1V1 Q6NS85 Q3UKD0 Q3UKF2 Q3TJN4 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase Sgk1; EC=2.7.11.1;AltName: Full=Serum/glucocorticoid-regulated kinase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 431 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sgk1	serum/glucocorticoid regulated kinase 1	60	107	3	92

Sequence references in MGI

J:55478 Naray-Fejes-Toth A, et al., sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels. J Biol Chem. 1999 Jun 11;274(24):16973-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:156956 Di Pietro N, et al., Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1. Mol Endocrinol. 2010 Feb;24(2):370-80
J:161794 Catela C, et al., Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Dev Dyn. 2010 Aug;239(8):2149-60
J:172878 Eylenstein A, et al., Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1). FASEB J. 2011 Jun;25(6):2012-21
J:176618 Lu M, et al., mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel. J Biol Chem. 2011 Sep 2;286(35):30647-54
J:182894 Mo JS, et al., Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. J Cell Sci. 2011 Jan 1;124(Pt 1):100-12
J:183019 He P, et al., Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids. Mol Biol Cell. 2011 Oct;22(20):3812-25