Sequence Detail

ID/Version

Q9WVE0 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Single-stranded DNA cytosine deaminase; EC=3.5.4.38 {ECO:0000269|PubMed:12692563, ECO:0000269|PubMed:23803409};AltName: Full=Activation-induced cytidine deaminase; Short=AID;AltName: Full=Cytidine aminohydrolase;

Provider

SWISS-PROT

Sequence

Polypeptide 198 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aicda	activation-induced cytidine deaminase	43	105	3	34

Sequence references in MGI

J:55852 Muramatsu M, et al., Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem. 1999 Jun 25;274(26):18470-6
J:82919 Chaudhuri J, et al., Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature. 2003 Apr 17;422(6933):726-30
J:172192 Okazaki IM, et al., Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7920-5
J:305767 Maeda K, et al., GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. J Biol Chem. 2010 Jul 30;285(31):23945-53