Sequence Detail

ID/Version

Q9WVE8 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Protein kinase C and casein kinase substrate in neurons protein 2;AltName: Full=Syndapin-2;AltName: Full=Syndapin-II; Short=SdpII;

Provider

SWISS-PROT

Sequence

Polypeptide 486 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	50	103	3	81

Sequence references in MGI

J:56265 Ritter B, et al., PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins. FEBS Lett. 1999 Jul 9;454(3):356-62
J:66805 Modregger J, et al., All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis. J Cell Sci. 2000 Dec;113 Pt 24:4511-21
J:101755 Braun A, et al., EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling. Mol Biol Cell. 2005 Aug;16(8):3642-58
J:114364 Cuajungco MP, et al., PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem. 2006 Jul 7;281(27):18753-62
J:158755 Shimada A, et al., Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II. FEBS Lett. 2010 Mar 19;584(6):1111-8
J:183061 Senju Y, et al., Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting. J Cell Sci. 2011 Jun 15;124(Pt 12):2032-40
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89