Sequence Detail

ID/Version

Q9Z0E0 Q91YH7 Q3TCW4 Q80TW1 Q9QUQ0 Q9CW81 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Neurochondrin;AltName: Full=M-Sema F-associating protein of 75 kDa;AltName: Full=Norbin;

Provider

SWISS-PROT

Sequence

Polypeptide 729 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ncdn	neurochondrin	30	103	3	13

Sequence references in MGI

J:54929 Ishiduka Y, et al., Induction of hydroxyapatite resorptive activity in bone marrow cell populations resistant to bafilomycin A1 by a factor with restricted expression to bone and brain, neurochondrin. Biochim Biophys Acta. 1999 May 6;1450(1):92-8
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:86413 Mochizuki R, et al., Targeted disruption of the neurochondrin/norbin gene results in embryonic lethality. Biochem Biophys Res Commun. 2003 Oct 31;310(4):1219-26
J:90574 Istvanffy R, et al., Expression of neurochondrin in the developing and adult mouse brain. Dev Genes Evol. 2004 Apr;214(4):206-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:99914 Dateki M, et al., Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure. J Biol Chem. 2005 May 27;280(21):20503-8
J:139152 Schwaibold EM, et al., Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1. Biochem Biophys Res Commun. 2008 Aug 29;373(3):366-72
J:155805 Wang H, et al., Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling. Science. 2009 Dec 11;326(5959):1554-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87