Sequence Detail

ID/Version

Q9Z0F4 Q3TN80 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Calcium and integrin-binding protein 1; Short=CIB;AltName: Full=Calmyrin;AltName: Full=DNA-PKcs-interacting protein;AltName: Full=Kinase-interacting protein; Short=KIP;

Provider

SWISS-PROT

Sequence

Polypeptide 191 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cib1	calcium and integrin binding 1	123	103	3	17

Sequence references in MGI

J:53819 Saito T, et al., Structure, expression profile, and chromosomal location of a mouse gene homologous to human DNA-PKcs interacting protein (KIP) gene. Mamm Genome. 1999 Mar;10(3):315-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114645 Yuan W, et al., CIB1 Is Essential for Mouse Spermatogenesis. Mol Cell Biol. 2006 Nov;26(22):8507-14
J:141569 Zayed MA, et al., CIB1 regulates endothelial cells and ischemia-induced pathological and adaptive angiogenesis. Circ Res. 2007 Nov 26;101(11):1185-93
J:163320 Heineke J, et al., CIB1 is a regulator of pathological cardiac hypertrophy. Nat Med. 2010 Aug;16(8):872-9
J:166321 Naik MU, et al., CIB1 deficiency results in impaired thrombosis: the potential role of CIB1 in outside-in signaling through integrin alpha IIb beta 3. J Thromb Haemost. 2009 Nov;7(11):1906-14
J:181770 Kostyak JC, et al., Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migration. Blood. 2012 Jan 19;119(3):838-46
J:262464 Michel V, et al., CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival. EMBO Mol Med. 2017 Dec;9(12):1711-1731
J:280151 Wang Y, et al., Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice. Front Mol Neurosci. 2017;10:401
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89