Sequence Detail

ID/Version

Q9Z0F5 Q8CHQ2 Q3TUM6 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Cholesterol 25-hydroxylase {ECO:0000305}; EC=1.14.99.38 {ECO:0000269|PubMed:9852097};AltName: Full=Cholesterol 25-monooxygenase; Short=m25OH;

Provider

SWISS-PROT

Sequence

Polypeptide 298 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ch25h	cholesterol 25-hydroxylase	21	98	3	10

Sequence references in MGI

J:51514 Lund EG, et al., cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism. J Biol Chem. 1998 Dec 18;273(51):34316-27
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:188276 Yi T, et al., Oxysterol Gradient Generation by Lymphoid Stromal Cells Guides Activated B Cell Movement during Humoral Responses. Immunity. 2012 Sep 21;37(3):535-48
J:254237 Dang EV, et al., Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation. Cell. 2017 Nov 16;171(5):1057-1071.e11