Sequence Detail

ID/Version

Q9Z0J4 Q3UR10 Q64208 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Nitric oxide synthase 1 {ECO:0000312|MGI:MGI:97360}; EC=1.14.13.39 {ECO:0000250|UniProtKB:P29476};AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS; Short=N-NOS; S

Provider

SWISS-PROT

Sequence

Polypeptide 1429 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nos1	nitric oxide synthase 1, neuronal	124	149	3	19

Sequence references in MGI

J:32915 Silvagno F, et al., Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle. J Biol Chem. 1996 May 10;271(19):11204-8
J:39582 Ogura T, et al., Structural diversity of neuronal nitric oxide synthase mRNA in the nervous system. Biochem Biophys Res Commun. 1993 Jun 30;193(3):1014-22
J:77278 Fang M, et al., Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron. 2000 Oct;28(1):183-93
J:93572 Joubert L, et al., New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4(a) receptor splice variant: roles in receptor targeting. J Cell Sci. 2004 Oct 15;117(Pt 22):5367-79
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121594 Chanrion B, et al., Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8119-24
J:125938 Mustafa AK, et al., Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2950-5
J:139346 Brenman JE, et al., Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Cell. 1995 Sep 8;82(5):743-52
J:180208 Erez A, et al., Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Dec;17(12):1619-26
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89